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 There's plenty of good news about coffee and    liver disease.  
 After so many years of being told that coffee is bad    for us, it’s hard to keep up with the more recent studies that tell us    the opposite.  
 Whether it’s diabetes, colon cancer or the effects of    smoking, all we hear now is good news about coffee.  With regard to liver disease, consider these two    news items:  Coffee reduces risk of death from liver disease    
 Drinking three cups of coffee daily may reduce the    risk of mortality from liver cirrhosis, suggest researchers in Norway.    The team from the Norwegian Institute of Public    Health in Oslo followed up 51,306 adults who underwent screening for    cardiovascular disease from 1977 to 1983. During this time, 53 deaths    were cirrhosis-related, and 36 of these deaths were attributed to    alcoholic cirrhosis. The relative risk of liver cirrhosis, adjusted for    sex, age, alcohol use and other major cardiovascular risk factors,    seemed to be reduced by 40 per cent for those drinking three daily cups    of coffee. For alcoholic cirrhosis the results were identical, reported    the researchers in this month's Annals of Epidemiology.  “The present study confirms the existence of an    inverse association between coffee consumption and liver cirrhosis,”    concluded the researchers, although they could not explain which    component of coffee was producing the protective effect. The beneficial    ingredient is unlikely to be caffeine however.  Source: nutraingredients-usa.com, 2005  
 
 Coffee, Caffeine Consumption Associated With    Reduced Liver Disease  
 A U.S. population study of 5,944 adults conducted    by researchers at the National Institute of Diabetes and Digestive and    Kidney Diseases (NIDDK) has found a strong association between coffee    drinking and caffeine consumption and a lower risk of liver injury in    persons at high risk for liver disease.  The researchers defined the high-risk population    as those who reported being heavy drinkers of alcohol, or who had    hepatitis B or C, iron overload, were obese, or had impaired glucose    metabolism. Liver injury was defined as a serum alanine aminotransferase    (ALT) activity level in excess of 43 U/L.  The researchers reported that overall, the greater    the coffee consumption, the greater the association with liver    protection (P = .034 for the trend). The highest consumption noted was    more than two cups of coffee per day. Consumers of more than two cups of    coffee per day had an odds ratio (OR) for elevated ALT of 0.56 (95%    confidence interval [CI], 0.31 - 1.0); those who drank one to two cups    had an OR of 0.83 (95% CI, 0.49 - 1.4). Those who drank less than one    cup had an odds ratio of 1.4 (95% CI, 0.84 - 2.4), with zero cups being    assigned an OR of 1.0.  Source: Medscape Medical News, 2004  
 No miracle cure, but...  Nobody is suggesting that coffee will cure you of    liver disease, not now or in the future. But it’s reassuring to know    that the brew we enjoy so much has some very healthy attributes.  Coffee and liver disease is just one of the areas    where caffeine appears to play an active and positive role.  
 
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